Goshir Paljor Dhondrup (1427-1489) was born at Nyemo in Central Tibet. Under the guidance of the Sixth Karmapa Thongwa Dhonden, he received transmissions of the Kagyur, Tengyur, and many others. He was fully trained in buddhist philosophy and meditation by Karmapa, as well as by Bengar Jampal Sangpo and other lineage masters. Later, he was appointed as the General Secretary of the Karmapa. He offered his service to the activities of Karmapa and the lineage. Paljor Dhondrup is the first incarnation of Gyaltsab Rinpoche.
He passed into parinirvana when the Seventh Karmapa reached twenty-five-years, with many wondrous signs of accomplishments. He received the full lineage transmission from the Sixth Karmapa, which he fully passed on to the Seventh Karmapa, Chodrak Gyatso.